BossWe

1. This study investigates the relationship between critically low levels of magnesium in the blood (serum magnesium) and the risks of developing hypothyroidism and having positive anti-thyroglobulin antibodies. 

Wang, K., Wei, H., Zhang, W., Li, Z., Ding, L., Yu, T., Tan, L., Liu, Y., Liu, T., Wang, H., Fan, Y., Zhang, P., Shan, Z., & Zhu, M. (2018). Severely low serum magnesium is associated with increased risks of positive anti-thyroglobulin antibody and hypothyroidism: A cross-sectional study. Scientific Reports, 8, 9904. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028657/

2. The goal of this study was to find out if there is a connection between certain biochemical markers, ultrasound images, and musculoskeletal data in people with hyperthyroidism (a condition where the thyroid gland is overactive). The researchers also wanted to see if these aspects could be improved with the use of supplements like selenomethionine and magnesium citrate, and treatments like acupuncture and manual medicine methods.

Wang, K., Wei, H., Zhang, W., Li, Z., Ding, L., Yu, T., Tan, L., Liu, Y., Liu, T., Wang, H., Fan, Y., Zhang, P., Shan, Z., & Zhu, M. (2018). Severely low serum magnesium is associated with increased risks of positive anti-thyroglobulin antibody and hypothyroidism: A cross-sectional study. Scientific Reports, 8, 9904. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028657/

3. A Pilot Randomised Controlled Trial" aims to investigate how L-Theanine influences physiological responses in healthy male individuals.

Williams, J., McKune, A. J., Georgousopoulou, E. N., Kellett, J., D’Cunha, N. M., Sergi, D., Mellor, D., & Naumovski, N. (2020). The Effect of L-Theanine Incorporated in a Functional Food Product (Mango Sorbet) on Physiological Responses in Healthy Males: A Pilot Randomised Controlled Trial. Foods, 9(3), 371. https://doi.org/10.3390/foods9030371

4. This study found that people reported having greater sleep satisfaction after taking 450–900 mg of L-theanine daily for 8 weeks.

Sarris, J., Byrne, G. J., Cribb, L., Oliver, G., Murphy, J., Macdonald, P., Nazareth, S., Karamacoska, D., Galea, S., Short, A., Ee, C., Birling, Y., Menon, R., & Ng, C. H. (2019). L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial. Journal of Psychiatric Research, 110, 31-37. https://doi.org/10.1016/j.jpsychires.2018.12.014

5. In a review of five randomized controlled trials that included 104 participants, four trials linked L-theanine with reduced stress and anxiety in people experiencing stressful situations.

Everett, J. M., Gunathilake, D., Dufficy, L., Roach, P., Thomas, J., Upton, D., & Naumovski, N. (Date). Theanine consumption, stress and anxiety in human clinical trials: A systematic review. Journal Name, Volume(Issue) https://doi.org/10.1016/j.jnim.2015.12.308

6. L-theanine may contribute to improving attention, thus enhancing working memory and executive functions.

Baba, Y., Inagaki, S., Nakagawa, S., Kaneko, T., Kobayashi, M., & Takihara, T. (2021). Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study. Journal of Medicinal Food, 24(4), 333-341. https://doi.org/10.1089/jmf.2020.4803

7. The study investigated the effects of orally administered gamma-aminobutyric acid (GABA) on relaxation and immunity during stress in humans.

Abdou, A. M., Higashiguchi, S., Horie, K., Kim, M., Hatta, H., & Yokogoshi, H. (2006). Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans. BioFactors, 26(3),  https://pubmed.ncbi.nlm.nih.gov/16971751/

8. 5-HTP may counteract these hunger-inducing hormones, working to suppress appetite and help you lose weight

Heisler, L. K., Jobst, E. E., Sutton, G. M., Zhou, L., Borok, E., Thornton-Jones, Z., Liu, H. Y., Zigman, J. M., Balthasar, N., Kishi, T., Lee, C. E., Aschkenasi, C. J., Zhang, C-Y., Yu, J., Boss, O., Mountjoy, K. G., Clifton, P. G., Lowell, B. B., Friedman, J. M., Horvath, T., Butler, A. A., Elmquist, J. K., & Cowley, M. A. (2006). Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron, 51(2), 239-249. https://pubmed.ncbi.nlm.nih.gov/16846858/

9. In this study, 20 people with diabetes were randomly assigned to receive either 5-HTP or a placebo for 2 weeks. The results showed that those who received 5-HTP consumed approximately 421 fewer calories per day, compared to the placebo group.

Cangiano, C., Laviano, A., Del Ben, M., Preziosa, I., Angelico, F., Cascino, A., & Rossi-Fanelli, F. (1998). Effects of oral 5-hydroxy-tryptophan on energy intake and macronutrient selection in non-insulin dependent diabetic patients. International Journal of Obesity and Related Metabolic Disorders, 22(7), 648-654. https://pubmed.ncbi.nlm.nih.gov/9705024/

10. According to one study in 68 people, alterations in circadian rhythm were shown to contribute to seasonal depression, but taking melatonin capsules daily was effective at reducing symptoms. 

Lewy, A. J., Lefler, B. J., Emens, J. S., & Bauer, V. K. (2006). The circadian basis of winter depression. Proceedings of the National Academy of Sciences of the United States of America, 103(19), 7414-7419. https://pubmed.ncbi.nlm.nih.gov/16648247/