A recent report from major EU and US medical organizations clearly states there is no proven relationship between SIBO and IBS
“Key points
• The SIBO-IBS
hypothesis has stimulated significant research into the role of the microbiota in symptoms of DBGI but remains unproven.
• This hypothesis has resulted in serious unintended consequences, namely the use of poorly validated breath tests to diagnose SIBO and the resulting injudicious use of antibiotics.
• The lactulose breath test (LBT) is primarily a measure of intestinal transit and has very low sensitivity and specificity to diagnose SIBO.
• The glucose breath test (GBT) has better performance characteristics if the pre-test probability is high, as found in conditions underlying classical SIBO, but also has a high false-positive rate in DGBI.”
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A recent report from major EU and US medical organizations clearly states there is no proven relationship between SIBO and IBS
“Key points
• The SIBO-IBS
hypothesis has stimulated significant research into the role of the microbiota in symptoms of DBGI but remains unproven.
• This hypothesis has resulted in serious unintended consequences, namely the use of poorly validated breath tests to diagnose SIBO and the resulting injudicious use of antibiotics.
• The lactulose breath test (LBT) is primarily a measure of intestinal transit and has very low sensitivity and specificity to diagnose SIBO.
• The glucose breath test (GBT) has better performance characteristics if the pre-test probability is high, as found in conditions underlying classical SIBO, but also has a high false-positive rate in DGBI.”
https://onlinelibrary.wiley.com/doi/10.1111/nmo.14817
Very useful article!